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Principal Investigator

Francisco J. Quintana, Ph.D.
fquintana@rics.bwh.harvard.edu

Francisco J. Quintana, Ph.D. is a Professor of Neurology at the Center for Neurologic Diseases, at Brigham and Women’s Hospital, Harvard Medical School, and an Associate Member at the Broad Institute of Harvard and MIT.

Dr. Quintana, a graduate of the University of Buenos Aires (1999, Argentina), obtained his Ph.D. in immunology at the Weizmann Institute of Science (2004, Israel).  He received postdoctoral training at the Weizmann Institute of Science and at Harvard Medical School.  In 2009, Dr. Quintana joined the faculty of Harvard Medical School.

Dr. Quintana’s research investigates signaling pathways that control the immune response and neurodegeneration, with the ultimate goal of identifying novel therapeutic targets and biomarkers for immune-mediated disorders.  Dr. Quintana has published over 140 peer reviewed articles and book chapters. In addition, Dr. Quintana’s research has resulted in multiple patents which have been the foundation of three companies: ImmunArray Ltd, Alma Bio Therapeutics and AnTolRx Inc. Dr. Quintana is the Director of the course Autoimmunity at Harvard Medical School.

Dr. Quintana is the recipient of the Lady Anne Chain Prize for Academic Excellence and Scientific Achievements, the Junior Investigator Award from the National Multiple Sclerosis Society, the Pathway to Independence Award of the National Institute of Allergy and Infectious Diseases, the Award for Outstanding Research Achievement form Nature Biotechnology and the Tecan Award for Innovation, the Harry Weaver Award from the National Multiple Sclerosis Society, the Young Mentor Award from Harvard Medical School and the Milestones in MS research from the National MS Society and the AAI-BD Bioscience Investigator Award.

Investigators
Atsushi Kadowaki

Atsushi Kadowaki, M.D., Ph.D.
akadowaki@bwh.harvard.edu

Atsushi obtained his M.D. from Osaka University, Japan in 2005 and was certified as board of Internal medicine and Neurology after clinical trainings. Thereafter, he was interested in neuro-immunological diseases and conducted the research about gut environment-induced T cells on multiple sclerosis, using mouse and human samples (Takashi Yamamura lab) in the National Center of Neurology and Neuroscience (Tokyo). He obtained his Ph.D. of Medicine in 2017 (Osaka University). He joined Quintana lab as a research fellow in the end of 2017 and currently studying about environmental and genetic effects on astrocytes during CNS inflammation.

Hong

Hong-Gyun Lee, Ph.D.
hlee83@bwh.harvard.edu

Hong-Gyun received his Bachelor’s Degree in Life Science in 2013 from Hanyang University, Seoul, South Korea. Following his great interest in immunology, he worked in the lab of Dr. Je-Min Choi, identifying the role of antigen-independent CD4 T cells in Multiple Sclerosis. Hong-Gyun received his Ph.D. in 2019, and further joined the Quintana Lab in 2021, shifting focus toward neuroimmunology. He is now currently interested in understanding how microbial metabolites control astrocyte activation in CNS inflammation.

M.Wheeler

Michael Wheeler, Ph.D.
mwheeler0@bwh.harvard.edu

Michael Wheeler received his Bachelor of Arts degree from Johns Hopkins, where he worked in the lab of Hongjun Song studying adult neural stem cells in the hippocampus. He graduated in 2011 with honors in Neuroscience and a minor in Philosophy. He maintained his academic focus and began his Ph.D. work in Neuroscience at the University of Virginia under the mentorship of Chris Deppmann and Ali Güler. His thesis focused on neural circuit development and engineering novel electromagnetic tools to study the nervous system. Michael was awarded his Ph.D. in 2016 and joined the Quintana Lab later that year, where he shifted his academic focus toward Neuroimmunology. His current research focuses on the transcriptional regulation of macrophages and astrocytes in multiple sclerosis and glioblastoma. For fun, Michael likes trying new restaurants, going to museums, and watching movies at the Coolidge Corner Theater.

Federico Giovannoni

Federico Giovannoni, Ph.D.
fgiovannoni@partners.org

Federico received his Ph.D. from the University of Buenos Aires, Argentina. His research was focused on understanding how hemorrhagic fever-causing viruses evade cell intrinsic immunity. The recent outbreak of Zika virus, which has been shown to infect cells in the CNS, has sparked our interest into finding common pathways of disease for Zika virus and other neurologic conditions. During his postdoctoral research, he is focused on the role of AHR in different virus infections, and in the therapeutic modulation of the glioblastoma microenvironment by oncolytic viruses.

Camilo Faust

Camilo Faust Akl
cfaustakl@bwh.harvard.edu

Camilo is a half-German student from Venezuela with an interest for immunotherapeutic approaches to combat solid tumors. After completing his B.S. in Biotechnology at the Technical University of Berlin, he received a Master’s Degree in Immunology at Harvard Medical School and completed his thesis research at the Quintana Lab. As a PhD student, he is investigating immunological roles of glioblastoma-associated astrocytes by use of single-cell technologies. In his free time, he enjoys cooking, traveling, photography, concerts and sports.

Brian photo

Brian M. Andersen, M.D., Ph.D.
Brian_Andersen@dfci.harvard.edu

Brian Andersen is a neuro-oncology fellow at Massachusetts General Hospital, The Dana-Farber Cancer Institute, and Brigham and Women’s Hospital and a post-doctoral fellow in the Quintana lab. Brian earned his Bachelor’s of Arts in chemistry from Saint Olaf College before post-baccalaureate laboratory research work at the National Institutes of Health and the Norwegian University of Science and Technology (NTNU) as Fulbright Scholar. He then completed the Medical Scientist Training Program (M.D./Ph.D.) at the University of Minnesota, where he earned his Ph.D in neuroscience under the mentorship of Drs. John Ohlfest and Michael Olin. He then completed internship and neurology residency at Weill Cornell Medical Center in New York, NY. He joined the lab in August 2020, where he studies the biology of astrocytes and cellular interactions in the glioblastoma microenvironment. In his free time, he enjoys exploring Boston by bicycle, gardening, and listening to all kinds of music.

Gavin photo

Gavin Piester
gpiester@bwh.harvard.edu

Gavin received a BS in Biochemistry and a BA in Chemistry at the University of Rochester. While there he worked with Mark Noble studying the impact of genetic and infectious factors on lysosomal function within demyelinating disease. Following graduation, he worked on CRISPR/Cas9 and AAV gene therapy treatments for orphan diseases at Intellia Therapeutics and Pfizer Rare Disease respectively. He then returned to the University of Rochester School of Medicine & Dentistry to start an MD/PhD. Gavin joined the Quintana Lab in 2021 to complete the PhD portion of his degree where he will focus on modulating pathogenic activities of astrocytes and microglia in Parkinson’s Disease in collaboration with Ania Majewska from the University of Rochester. Outside of research, you can find him running along the Charles River, cooking, and playing trumpet in an orchestra.

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Joseph Rone
jrone@g.harvard.edu

Joseph received his B.S. from the University of Cincinnati where he studied both Neurobiology and Biomedical Studies. While there, he also conducted animal behavior research in the lab of Charles Vorhees where he focused on the effect of environmental toxins on transgenerational behavioral deficits. He gained an interest in Immunology while working as a technician in Roni Nowarski’s lab at Brigham and Women’s Hospital where he focused on the role of the liver endothelium in shaping Kupffer cell responses in sepsis. He joined the Immunology PhD program at Harvard Medical School in 2020 and subsequently the Quintana Lab in 2021 where he focuses on the role of innate immune cytokines in EAE.

Tomer

Tomer Illouz, Ph.D.
tillouz@partners.org

Tomer completed his B.Sc. (2013) and M.Sc. (2014) degrees in Neuroscience at Bar-Ilan University, Ramat-Gan, Israel. He then completed his Ph.D. (2021) in the lab of Prof. Eitan Okun, studying multiple aspects of the immune response in Alzheimer’s disease and Down syndrome. In his studied, Tomer assessed the efficacy of DNA-based immunotherapeutic approaches for targeting Amyloid-β in preclinical mouse models. Additionally, He developed several machine-learning based methods for unbiased quantification of spatial learning strategies in rodent cognitive testing. Tomer Joined the Quintana lab in 2022 as a Postdoctoral Fellow to study cell-cell communication in Alzheimer’s disease. He is a recipient of the 2018 Clore Israel Foundation Scholarship, the 2022 Annette Karmiloff-Smith and Michael Harpold Trisomy-21 Thesis award, and the 2022 EMBO Postdoctoral Fellowship.

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Joon-Hyuk Lee, Ph.D.
jlee355@bwh.harvard.edu

Joon-Hyuk received a Bachelor’s Degree in Life Science in 2016 from Hanyang University, Seoul, South Korea, graduating Summa Cum Laude. He then began working on his Ph.D. in Neuroscience in 2016. He was awarded his Ph.D. Degree in 2022 under the guidance of Dr. Won-Suk Chung, studying the phagocytosis of astrocytes in the adult brain. Joon-Hyuk joined Dr. Quintana’s Lab in 2022 as a postdoctoral fellow with a strong interest in astrocyte subsets that influence neurological symptoms. Joon-Hyuk has received numerous awards, including a Global Ph.D. Fellowship (NRF), SHIMADZU award (KSBMB), Da-Han award (KBRI), Commendation for Academic Excellence (Deputy Prime Minister of Korea) and is currently a NRF postdoctoral fellow. In his free time, Joon-Hyuk enjoys watching Korean TV shows with his wife and playing soccer.

Bioinformatics Specialist
Zhaorong Li

Zhaorong Li, M.S.
zli37@bwh.harvard.edu

Zhaorong works in the Quintana Lab as a bioinformatician and received his M.S. in Bioinformatics from Boston University and his B.S. in Biology and Applied Mathematics from Stony Brook University.

Laboratory Technician
Lena Srun Photo

Lena Srun
lsrun@bwh.harvard.edu

Lena Srun received her B.A. from Wellesley College, where she studied Neuroscience and Economics. While she was there, she conducted research on glutamate transporters in C. elegans. She joined the lab in late 2021 as a technician. In her free time, she enjoys visiting museums, baking, learning new languages, and making art.

Senior Administrative Associate
Janelle Weathers

Janelle Weathers, M.M.
jweathers@bwh.harvard.edu

Financial Manager
Matt Varley

Matt Varley, CRA
mvarley@partners.org

2006-2009      Mauricio F. Farez, M.D. / Resident in Neurology, FLENI, Argentina

2009              Andrezza Santiago, Ph.D. / Assistant Professor, Universidade Federal de Minas Gerais, Brazil

2009-2011      Silvio M. Viera, Ph.D. / Post-doctoral Fellow, Yale University

2009-2011      Roya Rahbari, Ph.D. / Advanced Economic Analyst, Citizens Bank

2007-2010      Roopali Gandhi, Ph.D. / Assistant Professor, Harvard Medical School

2010-2016      Lior Mayo, Ph.D. / Assistant Professor, Tel Aviv University, Israel

2011-2012      Ruxandra Covacu, Ph.D. / Assistant Professor, Karolinska Institute, Sweden

2011-2016      Ada Yeste, M.S.  / Post-doctoral Fellow, Barcelona, Spain

2012              Miri Gordin, M.S. / Graduate Student, Bar-Ilan University, Israel

2012-2013      Chun Cheih Chao, M.S. / Post-doctoral Fellow, Harvard Medical School

2012-2015      Ivan Mascanfroni, Ph.D.  / Group Leader, Abbvie

2012              Nadya Ali, M.S. / M.D. Student, Michigan State University College

2013              Leslie Cuellar, M.S. / Visiting Scientist

2013              Georges Guillaume, M.S. / Visiting Scientist

2013              Megan Rodgers, M.Sc. / Visiting Scientist

2013-2014      Lukas Bunse, M.D. / Post-doctoral Fellow, Heidelberg University, Germany

2013-2014      Swasti Barthi, M.Sc. / Visiting Scientist

2014-2015      Mauricio F. Farez, M.D. / Assistant Professor, FLENI, Argentina

2014-2016      Merja Jaronen, Ph.D. / Assistant Professor, University of Kuopio, Finland

2016-2017      Kalil Alves da Lima, M.S. / Visiting Scientist

2018-2018      Lydia Guo / Undergraduate Student

2020              Carolina Manganeli Polonio, M.S. / Visiting Student

2020              Jessica Pereira, M.S. / Visiting Student

2020              Joao Vitor Mahler Ferreira Oliveira / Visiting Student

2020              Pedro Henrique Fonseca de Castro / Visiting Student

2017-2020      Andreia Barroso, Ph.D. / Post-doctoral Fellow

2017-2021      Iain Clark, Ph.D. / Assistant Professor, UC Berkeley

2017-2021      Cristina Gutierrez-Vazquez, Ph.D. / Scientist, Regeneron

2019-2020      Gabriel Lipof, M.S. / Lab Manager

2020-2021      Agustin Plasencia / Lab Manager

2021              Claudia M. Rejano Gordillo, M.S. / Visiting Scientist

2021-2022      Lucinda Li / Lab Manager

2021-2022      Kylynne Ferrara / Visiting Student

2018-2022      Liliana Sanmarco, Ph.D. / Post-doctoral Fellow

2022              Dulce Aleman / Summer Student

2022              Pere Duart-Abadia / Visiting Student

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